Monday, January 25, 2016

How we should feel about donor eggs?

Some people have an option to choose donor egg or use their own, some people have to use donor's by medical reasons. But the question - how we should feel about donors egg bother women in both cases, because the child will get genetic set from the donor. This is why million women in the world have concerns about egg donation or refuse to use it at all. So lets try to deal with this question.
Yes, child is not going to get your set of genes. This is something what you will have to take for granted. But instead there are a lot of advantages. Such as:
·        Genetically donor’s material is flawless because it is checked on all kind of types of abnormalities;
·        Incubation periods kept necessary time (this eliminates a lot of problems which children carry through their lives, a lot of diseases in adult life are laid during the formation of the fetus).
Egg donors are healthy and young and it’s more important than you can think. For example even if woman at 45 can have perfect 8-10 follicles with eggs she have very low changes. In 2010 The Institute of Reproduction in Livingston analyzed more than 600 cycles of pregnancy. According to the results in the age of 42 chances to have a healthy child using their own egg is 34% when by using donor egg – 98%.
Some more interesting statistics on the frequency of conception and successful pregnancy:
·        Probability of success using donor egg – 65% (it slightly change with recipient age);
·        If you are from 29 to 59 your probability of successful conception, bear and give a birth is 55-65%;
·        Using your own egg reduces the this probability on 5% every year;
·        By the age of 42 your chances to get pregnant and bear your child with your own egg is about 7%.

All this is only about women who can choose – use their own egg or donor egg, but most of the patience who use donor eggs don’t have another choice ,they have indications for unconditional donation, such as lack of ovarian,  "lazy ovaries" syndrome, surgery, chemotherapy, genetic hereditary diseases, menopause.

12 comments:

  1. We used BioTexCom for this reason.
    All their packages are all-inclusive. Meaning they include: Accommodation. Meals. Medical procedures and medications. Medical and psychological examination of the surrogates. Payments to the surrogate. Transfers to and from the airport and the clinic. Donor eggs if needed – for no additional price!! Interpreter with you at the clinic on every visit. Legal help to obtain documents for the baby after it is born. Monthly ultrasound reports with pictures of your baby. English speaking coordinator who is considered to be your point of contact at the clinic. Moreover, all packages are paid in 5 intallments!! No need to pay the whole money sum at once. The last 2 installments are paid after the birth of your baby! Needless to say their ”guaranteed” refund if no luck.
    One more thing to add. Have you, guys, ever seen anywhere such prices like:
    1 IVF cycle for EUR 4,900.
    2 IVF cycles for EUR 6,900, meaning EUR 3,450 per cycle!
    5 IVF cycles for EUR 9,900, which is EUR 1,980 per cycle!!
    Besides, all of the packages include donor eggs, ALL medications needed, transfer from/to the airport and from/to the clinic, accommodation, meals, interpreter services.
    This definitely blews away!

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  2. Egg issues are always agonising. January 2019, we had our follow up appointment and found out my egg quality sucks. I’m 31 years old but its like my eggs are that of someone in their mid 40’s and older. My Dr recommended we only do one more round of IVF. if it failed again with the same poor egg quality issue there would likely be no point in trying for the third round. as I would more than likely have the same issue. After that appointment we decided we will go for the second IVF round. so I have been on a highish dosage of Q enzyme 10 and DHEA. hoping it can help with the egg’s quality. I need to take all of this for three months then in April (I now only have one month to go) we will do our last round of IVF. Since the beginning of December 2018, I have also been doing weekly fertility acupuncture to try to help my body out. I'm not sure whether this approach helps me. Everything we need now is me producing some perfect eggs for ivf. They're currently stimulating my ovaries. If lucky, they'll retrieve some eggs to fertilize later in the lab. And then God help my small embies to make their home inside our surrogate.

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  3. I believe it's a huge pro to keep emotional well being, if you see what I mean. We've been through donor egg IVF route too. Passed it overseas. Got luck after 2 shots. Seems we got to the clinic with the well known aim - a healthy child through any means - be this own egg or donor's. We were emotionally ready we'll have to use donor egg 99% and our dr just reassured us. Dr Elena Mozgovaya was always kind and helpful and understanding. she made the ''medical part'' the best explained and perfectly guided. We're so much thankful for this. I believe being in right med hands is just crusial point.
    Also I am premature ovarian failure and have been taking DHEA for a while now. I still randomly have periods, but have never had signs of ovulation. Even with DHEA and all the supplements I have seen recommended, my numbers continue to get worse, as did my hot flashes. I am still hormonally an old women. I finally gave in and went on HRT. Physically, I feel substantially better. My Dr did recommend DHEA, saying it could slow my progression to full blown menopause, but will not reverse my condition. So it has some proven benefits, but I do not think it can reverse menopause.

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    Replies
    1. After three failed IUI shots, one failed ivf shot with own eggs we are going straight to egg donation route. Because of high prices home we applied for treatment overseas. This way we can choose from their donor database. I really don't want to waste more time, so we'll pass ivf#2 hopefully in Sep. I should say, I'm having a tough day.  Can't say why, feeling overwhelmed with all sort of thoughts..I feel so anxious..Just cought myself on the thought..When I was going through previous cycles I just knew/believed it was going to work. I tried to focus on what I wanted to do with my children..I did endless research into what products I wanted for them when they were born.. This did calm me down but now it doesn't. All our previous attempts turned out to be huge failure. And now I'm afraid to imagine things like that..Sorry for this vent..

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  4. Oh, yes, ladies, have you heard anything about the mitochondrial donation method?? I thought this article might be interesting for you to read~
    https://biotexcom.com/a-unique-m
    ethod-to-get-pregnant-in-your-40s-with-your-own-eggs/.
    BioTexCom Center for Human Reproduction offers patients who are above 40 and for those, who suffer from low levels of AMH, an innovative program that makes it possible to get pregnant with their own eggs. Mitochondria replacement therapy is an innovation and a breakthrough in the field of ART and the fertility treatment. This program gives women, who underwent numerous unsuccessful IVF cycles, aged 40+, patients with low mitochondrial functional activity, an excellent chance to give birth to a child who shares a genetic relationship with her and her partner.
    Mitochondrion is one of the most important components of any living cell, including the egg. In simple words, mitochondrion is the cell’s energy station. Essentially, its work consists in supplying the cell with vital energy for its normal functioning. Women that went through multiple unsuccessful IVF attempts, as well as of older reproductive age, need to restore oocyte mitochondria in order to successfully become pregnant. A woman can become pregnant only if there are functionally active mitochondria in her oocytes. Donation of mitochondria will allow thousands of hopeless women to give birth to a healthy child through IVF using mitochondrial donation. To carry out such a procedure, an egg donor with a high functional activity of mitochondria, a patient, and sperm for in vitro fertilization are required. Healthy functionally active mitochondria are taken from a donor’s oocyte and integrated with the patient’s cells. Next, fertilization with sperm and transfer of a healthy embryo into the patient’s uterus is performed. Mitochondria donation is a unique assistive reproductive technology, which is basically the implantation of a healthy and functionally active donor mitochondria into the cells of an infertile patient, that provides the patient’s cell with the necessary energy and contributes to successful pregnancy..In conclusion, Mitochondrial DNA and Human DNA are different things. It only gives that necessary energy to the oocyst and helps with developing an embryo and make it stronger. DNA is in the core of the mitochondria, which are not used for donation. Therefore, genetically, mitochondria have no effect on the embryo. You get genetically realted to you baby! But your dr is to test your eggs by specific means, as if they are damaged genetically - there's no use in doing this unfortunately.

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  5. Hey, ladies. There are too many reasons for the failed cycles. I did some research on this poit earlier. Thorough nvestigation is half a deal in the process. If your cycle failes here are the questions you need to ask.
    Have you had all the necessary blood tests and scans to ensure that nothing’s been overlooked? Are you 100% satisfied that there are no underlying medical factors that are stopping your pregnancy, such as blocked fallopian tubes, thyroid, polyps, fibroids, low egg reserve or any other possible issues that could be at the root of the problem? Why not take our pre treatment checklist to your doctor or consultant to discuss further investigation.
    Do you have any immune issues? Has this been tested? When? Even a perfect embryo doesn’t guarantee success – conditions have to be right for the embryo to plant itself in the womb lining before the embryo starts to develop. Some women have over-active immune systems that make the body reject the implanted embryo after IVF.
    If your immune system is too zealous, it can kill off implanted embryos to defend you. This reaction needs to be suppressed during pregnancy to allow the embryo(s) to be accepted. Has this been looked into and tested for? Blood products with antibodies can suppress a faulty immune system, although the treatment is still experimental.
    Is your consultant satisfied that the drugs that were given to you before and during IVF worked as they should? Has he checked your body’s reaction to them? Are there any other drugs that might work better?
    For an embryo to implant itself in the womb lining, this lining (called the endometrium) has to be thick enough. (more than 8 mm) If your lining is too thin, the embryo will fail. This is a challenging problem. Treatments that can help thicken the lining, but they are not suitable for everyone.
    If you have end-organ damage which will not respond to oestrogens, sadly nothing can be done to remedy this. Surrogacy may be the best answer (success rates are high). For some women, another option is not to transfer the embryos but to freeze them, then see if the lining can be thickened before the embryo is placed back into the uterus. Sorry for this being too long, hope this helps.

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  6. Had already had failed IUI shots, one ivf shot with own egg. Trying to stay sane, but I'm finding it too difficult this particular day. I've already shared on another thread. Today I cought myselfon the thought..When I was going through previous cycles I just believed it was going to work. I tried to focus on what I wantedto do with my children and did endless research into what products Iwanted for them when they were born.. This did calm me down but nowit doesn't. All our previous attempts turned out to be huge failure.And now I'm afraid to imagine things like that..I know I shouldn't take it like this. We're about to start our next ivf cycle. Everyone keeps saying 'try to think positively - Donor egg will do it!' But this makes me even more anxious..Oh, lovelies, dreaming we are on the other side soon..Huge hugs to all on this path.

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  7. I've never felt at comfort with donor eggs. Surely, the state of things was that both of us wanted genetically related kids only. If no - then we'd more likely to accept the childfree living. I'm not saying this decision is easy either. 'Cause this way you cannot count on donor eggs/sperm any more. But this choice is purely personal. I know a lot of people, mainly from infertility boards saying they've used donor egg/sperms or even both. But for us this was just out of the question. We didn't want to do sth we'd regret in future. Moreover, our dr at Biotexcom felt pretty well about using my own eggs, though not many..She did count on them. Dh was luckily absolutely ok. So this was our won genetic material used for surrogacy plan. This program did work out! A year later we have nothing to regret about. If I could I'd go through the same way. Furthermore this was the best decision made ever!

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  8. In addition to donor egg, donor embryo as well as adoption are family building options that many older women can consider (although there are age restrictions imposed in certain types of adoption). In some cases, donor embryo is actually a preferred option because of the lower costs and, once embryos that are available for donation are identified, this family building approach can actually be quicker than donor egg (for example, in the time it takes to go from putting a family building plan in place to actually cycling). Older prospective parents may find support and best guidance in how to achieve their dream of parenting at fertility centers but also in the offices of attorneys, mental health professionals as well as through various resources committed to providing information on alternative family formation.

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  9. Statistics show that 30% of women who start trying to conceive are able to fall pregnant on the first menstrual cycle (1 month). 60% achieve it after 3 cycles (about 3 months), while 80% will get pregnant after 6 cycles (about 6 months). 85% of women are able to become pregnant after one year of unprotected sexual intercourse.
    If, after 1 year, and provided that you are 30 years old or younger, pregnancy does not occur, you should visit a fertility specialist. If you’re 35 years or older, this period is reduced to 6 months. So, if you find yourself in any of these situations, my advice is that you should definitely go for IVF. And definitely if you have problems with egg/sperm quantity and quality, you will more likely to need donor ones. Of course we may feel all possible feelings concerning it, but as far as we understand what we are doing this for - your mind will be getting more and more peace with that. We have our adorable naturally conceived DD. But this time found ourselves on surrogacy route with donor egg at Biotexcom clinic in Ukraine. We faced this problem once- And were trying to solve it together soon afterwards. I think this is how it all works.

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  10. Also you don't have to pass different procedures, like taking high impact hormones or undergoing ER, for example. During this process, sedation is always required. The eggs are then collected (Using a needle that will pass through the vagina and into each of the ovaries under the guidance of ultrasound.) All this sounds really invasive and uncomfortable to my ear!! Of course, dedicated IVF specialists stress that this is a minor procedure. It lasts around 15-20 minutes. But would you go through it for someone else, not yourself?!!
    Two days after fertilisation, normal embryos will be between two and six cells. Three days after fertilisation, normal embryos will be between seven and nine cells.
    On the fourth day of fertilisation, most normal embryos will have reached the morula stage (too many cells to count with a microscope). Then, after 16-20 hours have passed, they are checked to see if any eggs have been successfully fertilised.
    Finally, hormone medicines will be supplied to aid in preparation for lining the womb to receive the embryo. The usual process for this is via pessary, injection, or gel.
    So using donor egg definitely has its benefits. But I really doubt whether I could do all this for somebody else. So let me tell my thanks to all the donors for what they're doing for others.

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  11. Any donor (sperm, egg, embryo) should be expected to relinquish all rights to the gametes (or the embryos) as well as explicitly relinquish parental rights to children resulting from the donation. With sperm donation, this relinquishment is typically done through consents at the cryobank. With egg and embryo donation, it is recommended that relinquishment of donor rights be memorialized in a direct contract between the donor and the recipient. Of equal concern, though, is whether or not the parent who lacks in a shared genetic connection with the child will feel a parental connection, while this should be explored with a mental health professional experienced in collaborative reproduction …the best response I have to offer is the following quote from a parent of a donor conceived child:
    “The child who came into my life is the most beautiful, spirited child…he is the child I was meant to have and he fills me with love every minute of the day.”

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