Monday, October 24, 2016

Women freeze eggs to gain time to find the right partners study finds

Women are choosing to freeze their eggs to gain time to find the right partner rather than to pursue their careers, new research suggests.
Based on interviews with 31 heterosexual women who had frozen their eggs for non-medical reasons, researchers discovered that the greatest motivation was because the women said they had not found the right man to father their child.
“Women weren’t engaging with technology for their career, they didn’t necessarily seek to delay, [or] put off motherhood, but it was very much more about they wanted to pursue motherhood at the right time, in the right way, with this right partner,” said lead researcher Kylie Baldwin, of the ReproductionResearch group at the UK’s De Montfort University.
“Women’s use of this technology is often driven by their relationships with men,” said Baldwin. “Instead of it being focused on egg freezing being a women’s concern, I think it needs to be broadened - I think men need to be brought into the picture more and there needs to be a more well-rounded understanding about why women engage with this technology.”
Emily Jackson, professor of law at the London School of Economics and a specialist in reproductive issues, said that despite coming from a small sample of women the findings were consistent with reports from the limited number of other studies available.
“[The findings don’t] mean [egg freezing] is not entirely unrelated to work, in the sense that the reason why one might find oneself 38 and single might have something to do with what career conditions were like in one’s 20s,” she said.
Egg freezing technology has taken off in the past five years or so, with increasing availability of a new approach, called vitrification, that has boosted success rates of conception.
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Tim Child, the medical director of the Oxford Fertility Unit, said that the findings chimed with his experience. “The majority of egg freezing requests are because someone wants to preserve their fertility so they feel as though if it is a few years before they meet the person they want to have a child with, and perhaps their fertility has declined to an extent where that might be more difficult to happen, at least they have got some fertility frozen in time,” he said.
Child also says that the sample size does not undermine the results. “You can base such studies on quite small numbers if the studies are conducted to a high standard.”
While the proportion of women freezing their eggs is still low, numbers are growing. According to the UK’s Human Fertilisation and Embryology Authority (HFEA), 816 British women underwent treatment to freeze their eggs in 2014, compared to 652 women in 2013. The approximate rate of live births using frozen eggs, based on those thawed in 2013, was 14%. Although, the report notes, “The success rate is affected by the age of the woman at the time her eggs were frozen and was considerably lower for women in the older age group.”
While the HFEA does not record detailed information on why the women chose to freeze their eggs, or the proportion who did so for medical reasons, in 2014 54.1% of those aged over 38 cited having no male partner as a reason, compared to 36.4% of those under the age of 38.
To delve into the issue, Baldwin interviewed women from the UK, US and Norway, recruited from advertisements, who said they had undergone egg freezing for non-medical reasons. Aged between 32 and 44 years old, all had been educated to degree level, with almost 40% having a postgraduate degree - a demographic typical of women who undertake such treatment, says Baldwin.
Baldwin says her results, which were presented at the British Science Festival on Wednesday, reveal that the primary reason why the women had opted to freeze their eggs was because they had yet to meet Mr Right.
“It wasn’t just about finding the right man, it was about finding the right potential father for their child,” she said. “They very much wanted to parent with their male partner who was committed to parenthood, who was going to perform that role of the hands-on father and would share the role of upbringing, the pleasures and pains of upbringing, equally.”
Other reasons, such as job instability or housing-related issues were also mentioned, says Baldwin, with 20% reporting an underlying health condition that contributed to their choice.
While several companies, including Apple and Facebook, offer egg freezing for female employees, Baldwin says she is not convinced by the approach. “Some of that use of egg freezing technology is often trying to solve the problem of older motherhood by not addressing the root cause, and the cause in many cases is this lack of a partner, lack of job security, not the desire to climb the career ladder,” she said.
With 37 as the average age of participants, the research reveals that women are leaving it until later in life to freeze their eggs, despite the decline in egg quality with age, says Baldwin. “Women need to be engaging with this technology for it to be the most effective before the age of 35, or perhaps even earlier,” she said.
But as Jackson points out, there are other considerations. Women in their early thirties still have a good chance of a natural pregnancy, she says, meaning that freezing eggs in their twenties could be an unnecessary invasive and expensive procedure. What’s more, in the absence of special circumstances, current legislation only allows eggs to be frozen for a maximum of 10 years. “The 10 year time limit means that in a sense it is not sensible to freeze them early, even thought that might be clinically sensible, because they won’t be available to you [later],” she said.
Baldwin also warns that the idea of egg freezing should not be presented to women as a quick fix. Cheryl Fitzgerald, Consultant in Reproductive Medicine at Old St Mary’s Hospital, Manchester, agrees. “I think seeing egg freezing as an option when it is things like you haven’t got your house or your haven’t got your job sorted is a really, really bad message because the majority of those women will then not end up with a baby,” she said. 
“Egg freezing is obviously great for those women who have no other option, but I think it shouldn’t be something that women resort to at an early stage. I think society needs to change and facilitate women to have their babies when they are younger.”
While Fitzgerald stresses that it is up to individuals to decide whether or not to freeze their eggs, she warns against the idea of viewing the technology as a simple solution.
“I think it is quite dangerous to start suggesting that, by medicalising a social problem, we can cure it,” she said. “If you’ve not met your partner, you’ve not met your partner, but I think it is a really bad message to give out that actually now we can get round this by egg freezing, because the majority of those women will still not have a baby.”


15 comments:

  1. Egg freezing is an awesome option by all means. It is a method of fertility preservation, which allows women to freeze eggs for later use. Women undergoing egg freezing generally take medication for a number of days to increase the growth of the eggs before they are collected in a short theatre procedure.Egg freezing might be an option if you're not ready to become pregnant now but want to try to make sure you can get pregnant later.
    You can use your frozen eggs to try to conceive a child with sperm from a partner or a sperm donor. A donor can be known or anonymous. The embryo can also be implanted in the uterus of another person to carry the pregnancy (gestational carrier).
    You might consider egg freezing if:
    You have a condition or circumstance that can affect your fertility. These might include sickle cell anemia, autoimmune diseases such as lupus, and gender diversity, such as being transgender.
    You need treatment for cancer or another illness that can affect your ability to get pregnant. Certain medical treatments — such as radiation or chemotherapy — can harm your fertility. Egg freezing before treatment might enable you to have biological children later.
    You're undergoing in vitro fertilization. When undergoing in vitro fertilization, some people prefer egg freezing to embryo freezing for religious or ethical reasons.
    You wish to preserve younger eggs now for future use. Freezing eggs at a younger age might help you get pregnant when you're ready.

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    1. I've found this on the internet. The chance that a single frozen egg will lead to a live birth is about 2 to 12 percent, according to the American Society for Reproductive Medicine. That’s why doctors often recommend having a couple dozen eggs frozen to maximize success.
      Success is based on a number of factors, from a woman’s age to the quality of her partner’s sperm, Pfeifer said. According to one study published in the journal Fertility Sterility in May 2013, a 30 year-old woman with two to six thawed eggs had a 9 to 24 percent chance of one of those eggs progressing to a live birth, depending on the method of freezing. At age 40, that number dropped to between 5 to 13 percent.
      In a January 2013 report, ASRM said that egg freezing technology has “improved dramatically” and that it should no longer be considered experimental. But the study concluded that there wasn’t enough data to recommend egg freezing for the purposes of delaying childbearing. More data is needed on safety, efficacy, ethics, emotional risks and cost effectiveness.

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  2. This is what I've just shared through commenting the article. Seems quite a discussion.. Egg freezing can be beneficial for a number of reasons for women wishing to preserve their fertility for the future including: Women who want or need to delay childbearing in order to pursue educational, career or other personal goals. Women diagnosed with cancer. Women with objections to storing frozen embryos for religious and/or moral reasons. A woman in her prime reproductive years may feel confident about her family building timeline. Unfortunately, not every woman has a straightforward path to pregnancy, and some may wonder how long to wait before exploring fertility preservation. It takes approximately 3 weeks to complete the egg freezing cycle and is consistent with the initial stages of the IVF process including:
    1-2 weeks of birth control pills to temporarily turn off natural hormones (this step can be skipped if there is urgency, such as prior to cancer therapy).
    9-10 days of hormone injections to stimulate the ovaries and ripen multiple eggs.
    Once the eggs have adequately matured, they are removed with a needle placed through the vagina under ultrasound guidance. This procedure is done under intravenous sedation and is not painful. The eggs are then immediately frozen. When the patient is ready to attempt pregnancy (this can be several years later) the eggs are thawed, injected with a single sperm to achieve fertilization, and transferred to the uterus as embryos. if 10 eggs are frozen, 7 are expected to survive the thaw, and 5 to 6 are expected to fertilize and become embryos. Usually 3-4 embryos are transferred in women up to 38 years of age. We therefore recommend that 10 eggs be stored for each pregnancy attempt. Most women 38 years of age and under can expect to harvest 10-20 eggs per cycle.
    So the reasons women do it are various. Just like their expectations. To find the right man to create the family with is also a huge responsiblity. I cannot judge a single woman for this. Moreover, I think I'd do the same if not having my wonderful dh by side. We all are so different..

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  3. Not surprising. Reasons vary. Some women choose to freeze their eggs for medical reasons. Cancer treatment, for example, can be toxic to the ovaries and cause premature menopause. But it’s not all medical. About three-quarters of the women who freeze their eggs do so because they don’t have a partner. The process of retrieving eggs is identical to the first phase of in vitro fertilization, or IVF. The procedure goes like this: The woman receives a round of hormone injections that stimulate the ovaries to produce multiple eggs. This stage involves frequent visits to the fertility clinic, about five in 10 days, while the ovaries are regularly monitored by vaginal ultrasound. After roughly a week or two of hormone treatments, the eggs are retrieved.
    This is a great way to keep your fertility ''safe''.

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  4. These are the tips on how to produce a good number of eggs and then successfully use them with IVF treatment:
    The most important step is to look at the preparation of your body and mind for this up coming journey, a journey to create life , a journey to allow your baby to choose you as parents. Here are some of the ideas quite popular on the internet. A detox can be a really good way to get your body back into balance and ready for the IVF journey. Getting rid of all those toxins you have build up in your body over the years.
    Then a well balanced diet will absolutely help your chances of success. Try and prepare this before the transfer. Take part in the fertility diet to enhance your reproductive organs and ensure good quality blood supply to the uterus. Good quality blood supply to the uterus increases protein and nutrient secretion around implantation, which your embryos will love.
    Get your partner on the Sperm Diet. IVF fertilisation rates increase with good quality sperm.
    Acupuncture is now, without a doubt, one of the best ways to enhance your success rates. It will reduce your stress, enhance your ovarian function, and increase blood supply to your reproductive organs. Plan an acupuncture treatment on the morning of transfer and one for the afternoon. Studies have shown that women who had acupuncture before and after embryo transfer had a 44% success rate per cycle compared to 29% amongst those who did not. Other therapies such as reflexology, hypnotherapy, yoga, or massage can also help. Alos the feel-good factor and endorphin buzz produced by regular sexual intercourse can really help to alleviate stress.
    Take a good quality multi-vitamin and mineral supplement which contains vitamins A, B, E and C complex, zinc, magnesium, selenium, iron and Co-enzyme Q10. which play a vital role in the fertilisation and implantation process. Essential fatty acids are vitally important. Wheat Grass to keep your FSH in check and Royal Jelly to nourish your egg quality. Finally Folic acid, make sure you are getting enough folic acid in your everyday diet as research shows this prevents neural tube defects, such as spina bifida.
    Hope this helps.

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  5. So it was about finding the right potential father for their child. It's very difficult to find a partner who is committed to parenthood. Who is going to perform that role of the hands-on father. Who will share the pleasures and pains of upbringing equally. So it is because ladies want to find a man who is Mr. Right one and will be a good father for the child. And not only for a child. But for the second half too. All in all, this all is such a complicated question. We all have different paths. But what makes us wise people is that we think of the future. And are trying to do our best to prepare.
    As far as I know, first time women egg freezing was introduced was for cancer patients who was at risk of loosing their ability to reproduce because of the invasive treatment. Nowadays however the egg freezing procedure is available for women without any medical reasons required. All over the world each year more and more women are choosing to freeze their eggs.Unfortunately, egg freezing does not however guarantee pregnancy. According to research the average age of women who freeze their eggs is 38 which is when fertility declines rapidly and it is definitely much too late if you want to have high chances for pregnancy. Not to mention that pregnancy so late in life is a difficulty by itself..

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    1. Right. Though there are far more reasons to freeze if there's the opportunity. I guess I figured that if I had good ovaries and a good uterus this would have work out since we skipped over my tubes. I did some research and I read that usually it takes a couple rounds before people are successful with ivf. After two years of being on this roller coaster my positivity had really gone down. All of my friends had babies of their own. so I just felt like they really didn't know what I was going through and how depressing it was. My husband had been great and so positive through that whole thing. but I just felt like I had been so focused on this! I just wanted to go into the next transfer with a clear mind and body. I was trying to get in touch with God again and to trust that he had a plan for me. but it was just hard because he lets me get pregnant but they took it away from me every time and just didn't understand why..

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  6. Would like to say a word for. Keeping fit is vital for treatments. Whilst undergoing them our bodies are ovewhelmed with stress and medications so we need them healthy and fit to boost chances. Here's what I found recently. Thought it's useful to consider. Exercise plays an important role in fertility, specifically, over-exercise. Studies show that women who reported regular exercise had a similar live birth rate compared to women who did not exercise. However, women who exercised four or more hours per week for 1-9 years were 40% less likely to have a live birth! Also three times more likely to experience cycle cancellation. And twice as likely to have an implantation failure or pregnancy loss compared to women who did not report exercise. However, compared to women who did not exercise, women who exercised regularly for 1-5 years were at greater risk for failure of cycle stimulation, implantation failure, and failure to develop a live birth after a chemical pregnancy!! I was really estonished to read this myself! As it might sound not logic. We all think keeping physically fit is great. And it is but for appropriate extent! Thankfully the negatives can be easily prevented though with the incorporation of active recovery into training and the gradual varying of intensity and volume of training. One should be aware of a good dr's guidance whilst training.

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  7. Oh God! I'm so sorry for that I haven't done this years before!! This way I'd have my own healthy eggs which we could use with ivf. But we never think in advance. I never think, will correct here.. I've never thought I'd find myself one day in a fertility clinic hall waiting for the appointment. 
    I've always envied fertile ladies with all their easy kids. My infertility issues caused us much pain and grief. I got this to the core of my being.
    Now full disclosure. I had one kid naturally at 39 yo. So I had nothing to complain about. But at 45 when I started to try to have a sibling for her, I suffered 6 miscarriages in a row!! Testing showed I could probably conceive again which I did! But I had other issues Clotting disorder among other things. So I did four rounds of IVF and got 12 eggs and 8 embryos. 4 of those were profoundly abnormal!
    So I did four expensive rounds of injectables and nothing. So it was down to donor egg or no child. Slowly I came to terms with it.nI don’t even think now I’m 100% comfortable. But I think I am there. Here one should take as much time as needed. Feelings are so valid. Something you just picture your whole life has been taken away from you. Something very precious. We were able to have a nice lady to donate at Biotexcom clinic. Though poor thing she got sick from donating and was hospitalized and very ill for a week after that. I'm so thankful for what this lady had done for us! So the joy was sucked out of even that. I’m forever changed by the entire experience but I’m now 9.5 weeks pregnant with a boy or a girl. Not sure yet. I wanted sth form my parents and me involved. And am blessed I could still use my body to carry my little one. I know I’ll be ok as soon as I hold the baby but this took me around four years to come to terms with egg donation. Here's one more example how tricky fertility might be to us. I also don’t want to give false hope to somebody but a friend of mine was told at 38 she would never have her own bio child and she did IVF. She got normals and delivered a girl two years ago. Then pregnant naturally at 44 again and delivered another girl this February. So while we can’t bank on that, ultimately it’s God or the Universe and a good clinic who decides this!

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  8. Firstly, I feel I need to tell my story here to go further with thoughts on the issue. After years of unsuccessful ttc we passed testings and had five IUI's resulting in failure. Further testing done and the following year I found out that I have low egg count. amh test found only less than 2 of my eggs were left at age 35. (And a normal egg count at this age is known to be 34-40.) Dh's sperm dna analysis indicated he has no drills in his sperm. This way we got two huge issues and explanations why no luck conceiving naturally. Then we started first mock ivf cycle. Some time later we got good news. I had four follies on the right and three follies on the left. I started meds. On day 6 only two follicles were at 1.1 cm which made me worry so much. Clinic told that if less than five are 1.2 cm that they would want to cancel the cycle. Actually they did as they failed to grow to needed size. Our next cycle harvested one embie only but it failed to implant. I was heartbroken. They told us we'd better turn to donor's egg for higher success rates. This step was the final one with our Irish clinic, so we felt we had to switch somewhere else for more affordable prices as we'd paid out of the pocket by that moment we couldn't afford more ivf cycles that way adding donor egg. We did a big research on the internet leading us to Biotexcom, Ukraine. We did hesitate first as it was going to be quite far from home and family's support but headed off as we could apply for 5 shots for 9900 euro only with guaranteed life birth. In case we fail they were to refund 100% money paid back! Which was a huge luck to have as we were safe of money loss and could spend it on following treatments in case. So this was a fresh breath for both of us. We were excited and nervous at the same time to start our program not knowing then it would bring us our lovely Andy girl. I know we want more kids. Probably we'll go the same path once more, not sure still. But I know I wouldn't freeze my eggs for future even if I could. (Moreover for the purpose of finding the best match – sounds weird for my ear.) All things in time. If you feel you are ready to have kids or to give kids to your partner now, then do it.

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  9. Yes it's hard but time should be not wasted. IMHO if lads have their eggs healthy and sound right now - they should use them. It's not the thing with infertility you can take your frozen eggs any time you want, harvest them into embryos and place back and know for sure they will make home. Your body doesn't get younger. Some of the inevitable changes are going on every passing year to woman's organism. they cannot be missed off. the thing is that you make love with your partner and get your kids naturally is better for me, than going through eggs extraction, freezing them, then taking your 'ideal' partner's sperm, combining it and putting the created embie in..Isn't this too long and tiresome!?? I would use my eggs just when time came. And I did actually but they turned to be useless at my 35 yrs then. We had finally to apply for donor egg overseas - with BIOTEXCOM. This way we got our girl because we had no natural options.I think ladies play a risky game. But its up to them to decide. Time could never be reversed. The only thing I wish those ladies might never regret things done.

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  10. Freezing eggs helps preserve your fertility until you find a partner you want to parent with. Or until you’re ready to become a single parent using a sperm donor. Though most experts do not recommend egg freezing after age 38. 'Cause the egg quality is usually on the decline. There are many personal and professional reasons why we may not want to bear a child when we’re at your peak fertility. Job issues, a recent divorce, financial uncertainty, or other challenges may mean we don’t want to get pregnant now. But we do want to have a baby later on when these issues are resolved. Frozen eggs can make biological parenthood possible through gestational surrogacy, if you are no longer able to carry a child due to health reasons. So taking all this into consideration, egg freezing is a nice option to have as back plan.

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  11. Thanks for sharing. Very interesting subject indeed. A woman in her prime reproductive years may feel confident about her family building timeline. Having a partner who also feels ready to conceive and a body that will cooperate with the plans will help expedite your goal of becoming a mother. Unfortunately, not every woman has an unimpeded path to pregnancy, and some may wonder how long to wait before exploring fertility preservation. Be this a search for the right partner or not (Reasons may vary dramatically) women do it. I know the story of a woman in my heighbourhood who had been battling cancer for a long time. And once she got to know all the seriousness of her disease, she consulted with a dr about her eggs preserving in a freezer, you know. She must have done it because she had no other way. We give birth to our kids not for our partners, dh but for ourselves, I'm just sure. We shouldn't waste time on looking for Mr Right to give birth to a baby. We do it for us, firstly. This is just one of the reasons. And it pains how many of them are there on the list. Anyway, we're lucky to have this option. I'd use if I could..

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  12. I've been through a lot of my own medical stuff with lots of medications so I don't know if I even can get pregnant- and that... is controlling me. Doctor's have largely rejected my concerns over the years, when I've brought up that I want to eventually get pregnant, they look at me from across the table, don't lift a single finger, and tell me that they see no reason why it would be difficult for me..Thanks to god, we've come across Biotexcom one day. 1 IVF cycle for EUR 4,900.
    2 IVF cycles, meaning EUR 3,450 per cycle!
    5 IVF cycles, which is EUR 1,980 per cycle!!
    Besides, all of the packages include donor eggs, ALL medications needed, transfer from/to the airport and from/to the clinic, accommodation, meals, interpreter services.
    This definitely blew us away!

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  13. This is what our kind dr at BTC explained to us some time ago. Despite significant advances in ART, women over 40 have a small chance and beyond age 45, women have almost no hope of achieving a successful live birth using their own eggs. Egg freezing definitely changes this. It allows women to better correlate their fertility desires with the career and relationship demands of today. Women with cancer or other conditions , probably represent the most important group who use this option. These women may now choose to freeze and store eggs. As opposed to men who are continually manufacturing new sperms, women are born with their ovaries preloaded with eggs. Again my dr at bio texcom explained that at birth, a woman's ovaries have about 2 million eggs. Later only about 400k remain. By the average age of menopause, 50, there will be only approximately 1k remaining. As they age, they suffer wear and tear. The delicate machinery that allows an egg to divide its chromosomes properly in half, breaks down over time. Abnormal numbers of chromosomes in an egg result in embryos which may not implant, may miscarry, or may result in the birth of a child with problems such as Down's syndrome. By the time a woman is 45, her risk of having a child with Down's syndrome reaches 1 in 30 live births. Her risk of all types of chromosomally-mediated birth defects is approx 1 in 10.

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